WebMay 21, 2024 · The data, presented at the Association for Cancer Immunotherapy (CIMT) 2024 Annual Meeting, continues to support the feasibility, comparative safety and pharmacokinetics of dose escalation of two CAR-T products, CCT301-38 (AXL) and CCT301-59 (ROR2), in a single patient population. WebJan 9, 2024 · During CCT301-59 production, subjects will receive a conditioning chemotherapy regimen of cyclophosphamide and fludarabine for the purpose of …
A Study of CCT301-59 CAR T Therapy in Adult Subjects …
WebBrief Summary. This clinical study is to investigate the safety and tolerability of CAR modified autologous T cells (CCT301-59) in subjects with recurrent or refractory solid tumors. Detailed Description. This is a single arm, open label, dose escalation clinical study to evaluate the safety and preliminary therapeutic efficacy of CCT301-59 T ... WebDescription This is a single arm, open label, dose escalation clinical study to evaluate the safety and preliminary therapeutic efficacy of CCT301-59 T cells in adult subjects with relapsed and refractory stage IV metastatic solid tumors (soft tissue sarcoma, gastric cancer, pancreatic cancer, bladder cancer etc.). patricia blessing tampa
NCT03960060 DrugSheet
WebMay 21, 2024 · The data, presented at the Association for Cancer Immunotherapy (CIMT) 2024 Annual Meeting, continues to support the feasibility, comparative safety and pharmacokinetics of dose escalation of two CAR-T products, CCT301-38 (AXL) and CCT301-59 (ROR2), in a single patient population. WebIn addition, 1359 phase 1 trials of anticancer drugs were initiated, with an AAGR of 23%. Sixty-three phase 1 trials were global multicenter trials, accounting for less than 5% of the total number. Most global multicenter trials were sponsored by Chinese pharmaceutical enterprises (32 of 48 sponsors [67%]). WebOct 21, 2024 · During CCT301-59 production, subjects will receive a conditioning chemotherapy regimen of cyclophosphamide and fludarabine for the purpose of … patricia blocksome nps