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WebMar 31, 2024 · We conducted a double-blind trial in which 35 patients with bipolar disorder type I or II in a depressive episode by DSM-IV criteria and in use of regular medication for the treatment of this phase of the disease were randomly allocated into two adjunctive treatment groups for 6 weeks: creatine monohydrate 6 g daily (N = 17) or placebo (N = … WebWhen excessive amounts of creatine is present in your brain, serotonin production may be suppressed, increasing the risk of developing some of the symptoms associated with low serotonin levels, such as weight gain, reduced insulin secretion, depression and diminished learning. Creatine and Dehydration WebAug 23, 2024 · In human trials, creatine has been studied extensively for the treatment of neuropsychiatric conditions other than depression—especially neurodegenerative … scotland where is it located