WebMar 20, 2024 · Mutations in the ADAMTS13 gene family have been reported to cause congenital thrombotic thrombocytopenic purpura (cTTP), a rare disease characterized by thrombocytopenia and hemolytic anemia. Nearly 150 causative mutations in ADAMTS13 have been identified; however, only a few of them were detected in Chinese patients. A 5 … WebJan 6, 2024 · cTTP is a subtype of thrombotic thrombocytopenic purpura (TTP), a rare and life-threatening disorder in which blood clots form in the small blood vessels throughout the body, and is caused by a...
Thrombotic thrombocytopenic purpura and pregnancy: …
WebFeb 26, 2024 · Laboratory Values During the Disease Course and Diagnosis of cTTP. The patient has been subjected to a series of tests in order to clarify his symptoms and to optimize his clinical management. The course of the most significant laboratory analyses are depicted in Table 1. No plasma products were given and no plasmapheresis was … WebDec 10, 2024 · A Phase 3b, Prospective, Open-label, Multicenter, Single Treatment Arm, Continuation Study of the Safety and Efficacy of TAK-755 (rADAMTS13, Also Known as BAX 930/SHP655) in the Prophylactic and On-demand Treatment of Subjects With Severe Congenital Thrombotic Thrombocytopenic Purpura (cTTP; Upshaw-Schulman … dallas market hall boat show
The International Hereditary Thrombotic …
WebApr 11, 2024 · Disease-causing mutations in cTTP occur throughout the ADAMTS13 gene, located on chromosome 9q34. 9 The ADAMTS13 gene (Figure 1) consists of 29 exons 10 encompassing 1427 amino acids, and 3 main categories of disease-causing mutations are seen: frameshift, missense, and nonsense mutations. To date, over 150 mutations have … WebJul 10, 2014 · Thrombotic thrombocytopenic purpura (TTP) is an acute, rare, potentially life-threatening disorder, presenting with thrombocytopenia, hemolytic anemia, … WebThrombotic thrombocytopenic purpura (TTP) is a rare blood disorder in which thrombi (blood clots) form in small blood vessels throughout your body. These blood clots … dallas market home and gift show