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Hif1a-as2

WebHá 2 dias · HIF1A-As2 is a KRAS-responsive lncRNA. We previously carried out a transcriptomic profiling analysis in H1299 cells with ectopic expression of KRAS WT or KRAS G12D (GSE124627) and identified 104 ... WebMechanistically, HIF1A-As2 epigenetically activates MYC by recruiting DHX9 on MYC promoter, consequently stimulating the transcription of MYC and its target genes. In …

hif1a-as2 PCR/Sanger Sequencing Primer pairs - Thermo Fisher …

Web66403 Ensembl ENSG00000111875 ENSMUSG00000019857 UniProt Q9Y294 Q9CQE6 RefSeq (mRNA) NM_014034 NM_025541 RefSeq (protein) NP_054753 NP_079817 … WebHIF1A-AS2 acted as a microRNA sponge that actively regulated the relative expression of SOX4 in sponging miR-30a-5p and subsequently increased the malignant phenotypes of renal carcinomas. HIF1A-AS2 showed a carcinogenic effect and miR-30a-5p acted as an antagonist of the anti-oncogene effects in the pathogenesis of renal carcinomas. shugar gourmet catering https://xavierfarre.com

Dynamic regulation of HIF1Α stability by SUMO2/3 and SENP3 …

WebIn short, HIF1A-AS2 facilitates the up-regulation of HIF-1α by sponging to miR-153-3p, whereby promoting angiogenesis in HUVECs in hypoxia. The present study revealed an … Web11 de jan. de 2024 · Besides, HIF1A-AS2 expression was also elevated in TNBC cell lines compared with the normal breast epithelial cell line. Moreover, high expression of HIF1A-AS2 was associated with lymph node metastasis, distant metastasis and unfavorable histological grade in TNBC patients. Web18 de jun. de 2024 · HIF1A-AS2 was significantly increased in cervical cancer tissue, and in the HPV- positive cervical cancer cells. Further investigation showed that the inhibition of HIF1A-AS2 suppressed cell proliferation, migration, invasion, and induced apoptosis, while up-regulation of HIF1A-AS2 revealed opposite results. the otp extranet

Long non-coding RNA HIF1A-AS2 facilitates adipose-derived stem …

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Hif1a-as2

LncRNA HIF1A-AS2 modulated by HPV16 E6 regulates apoptosis …

Web14 de mar. de 2024 · HIF1A-AS2 also was found to be highly expressed in atherosclerotic mice. Downregulation of HIF1A-AS2 inhibited inflammation by suppressing the levels of … Web31 de jul. de 2024 · The map illustrating mechanisms associated with lncRNA HIF1A-AS2-mediated inflammation in the atherosclerosis. LncRNA HIF1A-AS2 forms a complex with USF1, which is recruited into the ATF2 promoter to elevate ATF2 expression, thus promoting the development of atherosclerotic inflammation.

Hif1a-as2

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WebHIF1A-AS2-001: 533: No protein- lincRNA-The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants). … Web13 de nov. de 2024 · Long non-coding RNA HIF1A-AS2 modulates the proliferation, migration, and phenotypic switch of aortic smooth muscle cells in aortic dissection via sponging microRNA-33b. LncRNA HIF1A-AS1 Promotes Gemcitabine Resistance of Pancreatic Cancer by Enhancing Glycolysis through Modulating the AKT/YB1/HIF1alpha …

Web28 de mar. de 2024 · Moreover, by upregulating TRIM44 we were able to remedy the HIF1A-AS2 repression of apoptosis in HMCs. Thus, we conclude that cardiomyocytes … Web2 de abr. de 2024 · The area under the ROC curve was 0.865 for KCNQ1OT1, 0.852 for HIF1A‐AS2, and 0.967 for APOA1‐AS. Furthermore, the combination of lncRNAs resulted in a much higher AUC value of 0.990 for the prediction of CAD. Spearman's correlation analysis showed that APOA1‐AS was positively correlated with NT‐proBNP, ...

Web11 de abr. de 2024 · HIF1A-As2 expression, suggesting HIF1A-As2 and MYC form a double-positive loop that may robustly alter downstream genes Received: 4 October 2024 Revised: 18 March 2024 Accepted: 28 March 2024 Web13 de set. de 2024 · HIF1A-AS2 expression analysis in blood samples from advanced LUAD patients who received EGFR-TKI treatment showed that those with low HIF1A-AS2 expression had a good response (partial response, PR) to EGFR-TKI, whereas patients with high HIF1A-AS2 expression exhibited a poor response (stable disease, SD; Figure 1F).

Web26 de fev. de 2024 · Wu, R. et al. Long non-coding RNA HIF1A-AS2 facilitates adipose-derived stem cells (ASCs) osteogenic differentiation through miR-665/IL6 axis via …

Web17 de fev. de 2015 · Background Long noncoding RNAs (lncRNAs) have been recently shown to play important regulatory roles in fundamental biological processes, and many … the otp is set. cannot continueWebDownload scientific diagram HIF1A-AS2 Interactome Partners Belong to the Class of RNA-Processing Proteins from publication: The Long Non-coding RNA HIF1A-AS2 Facilitates the Maintenance of ... the otpfWeb11 de ago. de 2024 · The effect of HIF1A-AS2 on the expression levels of genes, which are associated with drug resistance and autophagy, was determinated by qRT-PCR analysis. … shugar creek onstedWeb8 de set. de 2024 · Mechanistically, SNHG15 directly targeted miR-141 , and HIF1A-AS2 sponged miR-429 to positively regulate PD-L1, leading to immune escape . Additionally, lncRNA NUTM2A-AS1 was found to bind to miR-376a to consequently enhance the expression of TET1 and HIF-1A, leading ... the ot practice cqcWebHIF1A-As2 Expression E 0 10 20 30 40 50 60 G1 S G2 ASO Ctrl ASO#1 % of Cell Population ** * G Cell Viability n.s. n.s. ASO Ctrl ASO#1 BEAS2B HEL299 1 0 2 3 Cell Viability ** H1299 1 0 2 ASO Ctrl ASO#1 DMSO Gefitinib ** ** ** CALU6 Cell Viability 1 2 ASO Ctrl ASO#1 ** ** DMSO Gefitinib * H1299 Cell viability ** ** DMSO Cisplatin 1 0 2 the ot platformWeb14 de mar. de 2024 · LncRNA HIF1A antisense RNA 2 (HIF1A-AS2) was proven to control HIF-1α mRNA expression because the known HIF-1 protein binding sites were expected to be situated in the HIF1A-AS2 promoter area . Additionally, it was described that LncRNA HIF1A-AS2 might stimulate angiogenesis in human umbilical vein endothelial cells … theo tpmpWebThe aberrant expression of hypoxia-inducible factor 1 alpha (HIF1A)-antisense RNA 2 (HIF1A-AS2) was found in various human cancers including breast cancer. The aim of … shugar foundation