Web15 jan. 2024 · Quinolones are bactericidal antibiotics that directly kill bacterial cells. They act on bacterial type II topoisomerases, DNA gyrase, and topoisomerase IV, inhibiting their function and converting them into toxic enzymes that produce permanent double … WebAbstract The present study was aimed to obtain a close insight into the distribution and diversity of antibiotic-resistant bacteria (ARB) and antibiotic-resistance genes (ARGs) …
Quinolones - SlideShare
Web31 dec. 2015 · Generic Name Levofloxacin DrugBank Accession Number DB01137 Background. Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of … Web7 mrt. 2024 · Fluoroquinolones are highly effective antibiotics with many advantageous pharmacokinetic properties including high oral bioavailability, large volume of … roblox that you don\u0027t have to buy
Bruker • Microbiology & Infection Diagnostics on LinkedIn: Two …
WebQuinolones MOA DNA inhibitors inhibit DNA gyrase, topoisomerase IV Metronidazole MOA DNA/RNA inhibitor List hydrophilic antibiotics CD Bag Colistimethate Daptomycin Beta lactams Aminoglycosides Glycopeptide (vanc) PK/implications of hydrophilic antibiotics small Vd --> poor tissue penetration renally eliminated --> nephrotoxicity Web1 dec. 2012 · The mode of action of quinolones involves interactions with both DNA gyrase, the originally recognised drug target, and topoisomerase IV, a related type II … Web25 sep. 2024 · Background Mycoplasma pneumoniae is a common pathogen that causes community-acquired pneumonia in school-age children. Macrolides are considered a first … roblox that you can watch