http://chem.ucalgary.ca/courses/350/Carey5th/Ch09/ch9-7.html WitrynaPhCHO, THF O Ph OH M= Li 16% yield M= MgBr 93% yield - Dehydration of the intermediate β -alkoxy- or β -hydroxy ketone can also serve to drive the reaction to the right. O O H O tBuO - Na +, tBuOH O O H O JACS 1979 , 101 , 1330 O Enolate Geometry - two possible enolate geometries O LDA, THF, -78°C O -Li+ O -Li+ + E - …
Problem Set 1 Functional Group Transformations Study Guide …
Witryna29 lip 2024 · If you really have to use DMSO, then I would place the NaH under inert gas in a flask as a suspension in THF and then slowly add the phosphonium salt as a solution in dmso. The reaction mixture should start immediately with the release of hydrogen gas. You have to regulate then the liberation of gas by the rate of addition of phosphonium … WitrynaYou have to exclude water from this reaction again, because the Grignard reagent will react with it. So in the first step, you want it to react with your carbonyl. And the … cheryl egberongbe
What are the products formed when CH3CH2OH reacts …
Witrynatine Brønsted base, while NaH has not been considered to work as a hydride donor. Recently, our group has serendipitously found that NaH can function as a unique hydride donor by its solvothermal treatment with sodium iodide (NaI) or lithium iodide (LiI) in … WitrynaNotes: Example 1 just shows a simple anti-Markovnikov addition of BH3 to an alkene.Examples 2 and 3 show the hydroboration of a cyclic alkene.Note the syn … Witryna21 lis 2024 · What does NaH and THF do? Typically NaH is used as a suspension in THF, a solvent that resists attack by strong bases but can solvate many reactive … cheryl egan obituary