Pseudotimede github
WebOct 1, 2016 · Motivation: Repeated cross-sectional time series single cell data confound … WebFor Slc39a10, both PseudotimeDE and Monocle3-DE yield small p-values (p < 1e − 6), while tradeSeq does not (p > 0.1). For Sst, PseudotimeDE yields larger p-values than tradeSeq and Monocle3-DE do.
Pseudotimede github
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WebApr 29, 2024 · PseudotimeDE yields the FDP closest to 0.05. d, i ROC curves and AUROC values of the five DE methods. PseudotimeDE achieves the highest AUROC. e, j Power of the five DE methods under the FDP = 0. ... WebMar 27, 2024 · PseudotimeDE is flexible in allowing users to specify the pseudotime inference method and to choose the appropriate model for scRNA-seq data. Comprehensive simulations and real-data applications verify that PseudotimeDE provides well-calibrated p -values essential for controlling FDR and downstream analysis and that PseudotimeDE is …
WebHere we propose PseudotimeDE, a DE gene identification method that adapts to various pseudotime inference methods, accounts for pseudotime inference uncertainty, and outputs well-calibrated p -values. Comprehensive simulations and real-data applications verify that PseudotimeDE outperforms existing methods in false discovery rate control and power. WebApr 22, 2024 · Here we propose PseudotimeDE, a DE gene identification method that adapts to various pseudotime inference methods, accounts for pseudotime inference uncertainty, and outputs well-calibrated p -values. Comprehensive simulations and real-data applications verify that PseudotimeDE outperforms existing methods in false discovery rate control …
WebApr 29, 2024 · Here we propose PseudotimeDE, a DE gene identification method that adapts to various pseudotime inference methods, accounts for pseudotime inference uncertainty, and outputs well-calibrated p -values. Comprehensive simulations and real-data applications verify that PseudotimeDE outperforms existing methods in false discovery rate control … WebPseudotimeDE. PseudotimeDE is a robust method that accounts for the uncertainty in pseudotime inference and thus identifies DE genes along cell pseudotime with well-calibrated p-values. PseudotimeDE is flexible in allowing users to specify the pseudotime inference method and to choose the appropriate model for scRNA-seq data. Latest News
WebThe pseudotimeDE R package (Song and others, 2024) does allow for an arbitrary pseudotime estimation technique, but it fits negative binomial generalized additive models (GAMs) by default, and...
http://jsb.ucla.edu/sites/default/files/news/PseudotimeDE_poster.pdf spurs 4th kitWebNov 17, 2024 · Finally, PseudotimeDE calculates a right-tail p-value for the gene from the gene’s test statistic in the original dataset and the approximate null distribution. Further detail of PseudotimeDE is described in Methods. Simulations verify that pseudotimeDE outperforms existing methods in the validity of p-values and the identification power. spurs 50th anniversary logoWebJun 20, 2024 · GitHub is where people build software. More than 94 million people use … spurs 5-3 chelsea