Web7 Apr 2024 · Thrombospondin-1 (TSP-1 or THBS-1), also known as thrombin-responding protein 1 or thrombin-sensitive protein 1, is a 150 kDa secreted member of the thrombospondin gene ... repeat binds CD36 and latent TGF-β, and the C-terminus binds CD47 (4). The Cys-rich segment Web10 Mar 2016 · Thus, MYC regulates CD47 and PD-L1 expression in multiple human tumor types. MYC can act as a general transcriptional amplifier (that is, it can generally increase expression of many genes rather than specific target genes), but dosage-dependent specific effects have been reported ( 32 – 36 ).

THBS1 regulates trophoblast fusion through a CD36

Web22 Aug 2024 · CD47 is ubiquitously expressed on the surface of cells and plays a critical role in self-recognition. By interacting with SIRPα, TSP-1 and integrins, CD47 modulates … Web21 Feb 2024 · CFH Binding to CD11b Inhibits MP Elimination Mediated by TSP-1 Activation of CD47. CFH can act as a cofactor of complement factor I (CFI) to cleave C3b into iC3b, … barclays personal banking

THBS1 Gene - GeneCards TSP1 Protein TSP1 Antibody

Web14 Apr 2024 · Recent advances provide evidence that the cellular signalling pathway comprising the ligand-receptor duo of thrombospondin-1 (TSP1) and CD47 is involved in … WebClearance by the reticuloendothelial system can be prolonged by the expression of anti-phagocytic surface proteins: CD47, THBS-1, and SIRPα . Upon reaching a target EVs may bind surface receptors initiating intracellular signaling or deliver their contents by endocytosis or fusion with the plasma membrane ( Figure 1 c) [ 48 ]. Web1 Dec 2024 · The authors demonstrated that CD47 lo MuSCs exhibit molecular and functional properties of self-renewing MuSCs and are more abundant in the muscle of … barclays pakistan bank